AdChem

PHARMACEUTICALS

Kornnac Capsules

No.439 Hebei Avenue, Chibi, Hubei Province, 437300, China

KornnacCaps — Advanced Functional Capsule Solutions for Global Pharmaceutical Manufacturing

Hubei Kornnac Pharmaceutical Co., Ltd. (formerly Hubei Humanwell Pharmaceutical Excipients Co., Ltd.) is a high-tech pharmaceutical manufacturer specializing in the development and production of high-quality empty capsules and functional capsule solutions for the global pharmaceutical and healthcare industries. With a strong focus on quality, innovation, and regulatory compliance, KornnacCaps has established a comprehensive quality management system in accordance with cGMP principles and holds internationally recognized certifications including HALAL, KOSHER, ISO 9001, and ISO 22000. The company has also completed EU registration and is registered with US FDA, demonstrating its commitment to meeting the stringent quality and regulatory expectations of international markets.

Over 400 mineral salts and more than 7,000 specifications. The specification count is the more meaningful number: it is the measure of how far a grade can be tailored.

ABOUT THIS PRINCIPAL

Innovation & Manufacturing Excellence.

With 100+ R&D engineers and fully automated production lines, KornnacCaps develops advanced capsule technologies and customized solutions to meet evolving pharmaceutical formulation needs. KornnacCaps offers titanium dioxide-free and SDS-free capsule solutions, supporting pharmaceutical manufacturers in adapting to evolving international regulatory requirements.

Manufactured without ethylene oxide (EtO) sterilization or added preservatives, KornnacCaps capsules are designed to support clean, modern, and internationally aligned pharmaceutical manufacturing.

KornnacCaps provides a wide range of gelatin, HPMC, Pullulan, Halal, acid-resistant, and liquid-filled capsules, with customized sizes, colors, and logo printing to meet specific product and market requirements.

With products exported to 60+ countries and regions, KornnacCaps combines international quality standards, R&D expertise, advanced manufacturing, and customization capabilities to support pharmaceutical customers worldwide.

The combination is powerful: Regulatory-compliant quality, Innovative capsule technologies, and Flexible customization, bringing international standards and Competitive price edge together under one manufacturing platform.

ADCHEM works with KornnacCaps to provide internationally compliant, high-quality capsule solutions, combining KornnacCaps’ advanced manufacturing and R&D capabilities with ADCHEM’s market knowledge and supply-chain expertise to support pharmaceutical customers across global markets.

FEATURED TECHNOLOGY

The technical case for KornnacCaps rests on regulatory-compliant manufacturing, advanced capsule technology, and customization capability rather than on a single capsule format. The four major categories of their product line are given below.

HARD GELATIN CAPSULES

Gelatin Capsule Types and DDP

Hard Gelatin capsules are offered as Gelatin Empty capsules, Halal/Kosher capsules, Enteric capsules, and 100% skin glue capsules. These capsules can be customized in terms of colour, capsule printing as per customer requirements. We are offering DDP local delivery for these capsules to our EU and USA customers.

VEGETABLE CAPSULES (VEGAN)

Vegetable Capsule Types and DDP

Vegetable capsules are offered as Health Food HPMC Empty capsules, Pharmaceutical HPMC Capsule, Pullulan capsules, Organic Pullulan capsules, and Sustained Release Capsule. These capsules can be customized in terms of colour, capsule printing as per customer requirements. We are offering DDP local delivery for these capsules to our EU and USA customers.

INNOVATION- SPECIAL CAPSULES

Liquid-Filled Capsules

Liquid-filled hard capsules technology is the innovative technology that offer a lot of innovation formulation options to the formulators. It comes in multiple dosage forms designed to cater customers innovative formulation needs and develop an innovative product for better market edge.

INNOVATION- SPECIAL CAPSULES

Pearl /SLS-Free/ TiO2 Free Capsules

Kornnaccaps offer customers SLS Free, TiO2 free and Pearl capsule options that can be further customized in terms of Capsule colour, capsule printing as per customer requirements.

Portfolio

The Humanwell portfolio.

Anaesthesia, sedation and analgesia products, supplied as APIs and finished dosage forms. All controlled-substance products are supplied only within the licensing framework of the destination market.

Remifentanil

What it is

Ultra short-acting synthetic opioid analgesic; DMF and CEP filed

Primary Use

Balanced general anaesthesia, procedural analgesia, intensive care sedation

What it is

Synthetic opioid analgesic; CEP filed

Primary Use

General anaesthesia and severe acute pain management

What it is

Citrate salt of fentanyl; CEP filed

Primary Use

Injectable anaesthesia and analgesia formats

What it is

Semi-synthetic opioid analgesic; CEP filed

Primary Use

Severe pain management, including patient-controlled analgesia

What it is

Short-acting benzodiazepine; CEP filed

Primary Use

Procedural sedation, premedication, induction of anaesthesia, ICU sedation

What it is

Centrally acting analgesic with a dual mechanism; CEP filed

Primary Use

Moderate to severe acute and chronic pain

What it is

Ultra short-acting benzodiazepine sedative and anaesthetic, developed in-house; commercialised in Europe as Byfavo through Paion

Primary Use

Procedural sedation and general anaesthesia where rapid, controllable offset is required

What it is

Water-soluble prodrug of propofol, the first approved in China

Primary Use

Intravenous anaesthesia and sedation with a modified pharmacokinetic profile

What it is

Further anaesthesia, sedation and analgesia molecules across the seven narcotic API lines

Primary Use

Available on request, subject to import licensing in the destination market

What it is

Sterile injectables and other formats produced across 26 finished dosage lines

Primary Use

Hospital supply, tender participation, and licensed in-market registration

LIQUID FILLED CAPSULES - CUSTOMIZED SERVICES

Advantages of Liquid-Filled Hard Capsules over Softgel.

Liquid-filled capsules offer a more flexible, stable, and customizable alternative to traditional softgels. They provide higher temperature resistance and support a wider range of innovative formats, including cap-in-cap, beadlet-in-liquid, and tablet-in-liquid capsules. Plant-based options can be formulated without added excipients or plasticizers, while customizable colour, size, and printing allow brands to create differentiated products. With an MOQ starting at 200,000 capsules, they also offer an attractive cost advantage for commercial production. Their significantly thinner shell, approximately one-tenth the thickness of a softgel, can support efficient drug release and bioavailability, while specialized acid-resistant, fast-release, and targeted-release technologies enable tailored solutions for demanding pharmaceutical applications.

Types of Liquid-Filled capsules

  • Cap-in-cap 
  • Beadlet-in-Liquid 
  • Tablet-in-Liquid Capsule

Formulation Support

ADCHEM’s technical team, together with KornnacCaps, can support customers in developing customized formulations for specific indications using liquid-filled capsule technology. Customers can also choose from a range of ready-to-use formulations, enabling a faster and more efficient path from concept to commercial development.

DDP – USA Supple

Post-operative and trauma analgesia, including formats suited to patient-controlled administration.

FDA Approval

Our liquid-filled capsules offer regulatory advantages for nutraceutical and food applications, helping customers navigate product registration and market entry more efficiently. The technology is designed to support FDA registration requirements, providing a practical pathway for customers looking to commercialize innovative liquid-filled products in the U.S. market.

DOCUMENTATION TO BE HELD

Regulatory documentation that supports the filing, not just the purchase order.

Kornnac Capsules products are supplied with the documentation required for regulatory submission, and supplier qualification.

Product and quality
  • Product specification sheet
  • Certificate of Analysis (CoA), batch specific
  • Safety Data Sheet (SDS / MSDS)
  • Compendial compliance statement against USP/NF, Ph. Eur., JP or BP as applicable
  • Analytical methods and method validation summary
  • Physical characterisation data: particle size distribution, bulk and tapped density, loss on drying
  • Stability data with retest period or shelf life justification
  • Drug Master File number with Letter of Access
  • Certificate of Suitability (CEP / COS) where filed
  • Written Confirmation for API import into the European Union
  • Manufacturing licence and site registration details
  • Open part documentation for inclusion in the applicant’s submission
  • Regulatory support commitment for market registration and variations
  • GMP certificate for the manufacturing site
  • Excipient GMP statement aligned to IPEC-PQG or EXCiPACT, for excipient grades
  • ISO 9001 certificate
  • Quality Agreement
  • Change control and prior notification commitment
  • Most recent regulatory inspection outcome summary
  • Completed supplier questionnaire or audit report

WORKING WITH ADCHEM

What ADCHEM adds to the Kornnac Capsule relationship.

SUPPLY CHAIN EXCELLENCE

DDP Delivery for Capsules across US and EU.

Providing a complete supply chain solution to customers by delivering product at the required time based on Annual sourcing contacts.

SUBMISSION-READY

Registration support

Completed documentation support for registration of product.

SINGLE-SOURCE QUALIFICATION

API or finished dose, one qualification

Where a customer needs both the API and the finished injectable, sourcing from one certified quality system materially shortens the qualification path.

COMPLIANT HANDLING

Cold chain and secure logistics

Handling, storage and chain-of-custody arrangements appropriate to scheduled and temperature-sensitive product.

QUICK FACTS
GROUP HEADQUARTERS
Chibi, Hubei Province China
GROUP HERITAGE
Part of China’s largest Humanwell Group
CAPSULE BUSINESS
Part of China’s largest Humanwell Group
R&D
Two advanced R&D facilities in Chibi and Wuhan.
CAPACITY
100,000 + m 2 Production site
REGULATORY
EU GMP, USDMF Filled, Easy registration with USFDA.
INTERNATIONAL FOOTPRINT
Exports going to more than 60 countries globally.
GLOBAL CERTIFICATIONS
ISO22000, ISO9001, HALAL Indonesia, Kosher, EU GMP, FDA. ICH-Q10, IPEC-GMP
Certifications
COSMOS Certified grades
Ecocert Certified
Vegan-aligned lines
Halal-aligned grades

Licensed capability, certified lines, and a real pipeline.

Three ways to start: a technical enquiry, a regulatory documentation request, or a conversation with a specialist who understands the licensing position in your market.

Request a Sample

Any product in the portfolio

Request Technical Data

Full technical library

Talk to Our Specialist

Someone who knows the chemistry first

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