COSMETICS & PERSONAL CARE
Mibelle Biochemistry
Buchs, Switzerland · Est. 1991
Plant-derived science at the frontier of skin biology.
Mibelle Biochemistry has spent more than three decades turning naturally derived plant compounds into functional, high-bioavailability cosmetic actives — backed by clinical studies, peer-reviewed publications, and the regulatory documentation brands need to make credible claims.
- Cosmetics & Personal Care
Over 400 mineral salts and more than 7,000 specifications. The specification count is the more meaningful number: it is the measure of how far a grade can be tailored.
ABOUT THIS PRINCIPAL
Three decades of plant science in a bottle.
Mibelle Biochemistry was founded in 1991 in Buchs, Switzerland by Dr. Fred Zülli. Operating independently within the Mibelle Group — Switzerland's largest manufacturer of cosmetic finished goods — the company has earned a global reputation for science-backed innovation in skin beauty, healthy ageing, hair care, and beauty-from-within nutraceuticals.
Mibelle's actives are formulated for premium personal-care brands worldwide, with a scientific dossier behind every product — clinical studies in vitro and in vivo, peer-reviewed publications, and the marketing tools formulators need to position their claims with regulators and end consumers alike. The result is an active ingredient company that behaves more like a biotech firm than a cosmetic raw-material supplier.
"Mibelle's chemistry is distinct because the science behind each active is demonstrable — not just a certificate of analysis, but a clinical dataset that a brand can put behind a claim and a regulatory submission."
ADCHEM holds Mibelle Biochemistry distribution in a defined set of regional markets, supported by stocking close to our personal-care customers and a formulation team in Bergamo and Lahore that can integrate Mibelle actives into a finished prototype within weeks. Customers get the Swiss science with regional logistics behind it.
FEATURED TECHNOLOGY
PhytoCellTec™ — and the encapsulation science that makes it work.
Mibelle's signature is PhytoCellTec™ — a proprietary plant cell culture technology that enables the large-scale cultivation of callus (stem) cells from rare and protected plant species. The platform unlocks actives that would otherwise be impossible to harvest at industrial scale, including a recent extension into PhytoCellTec™ Exosomes for skin rejuvenation.
Beyond PhytoCellTec™, Mibelle's encapsulation expertise — liposomes, lipid carriers and biopolymer encapsulation systems — is a core formulation enabler. The company's biochemists stabilise, modify and encapsulate naturally derived molecules to deliver real performance in a finished product, not just a label claim.
Core platform
PhytoCellTec™
Plant stem-cell culture technology — cultivating callus cells from rare species at industrial scale. Anti-ageing, longevity, and skin rejuvenation applications. Recent extension into PhytoCellTec™ Exosomes.
Delivery system
Encapsulation technology
Liposomes, lipid carriers, and biopolymer encapsulation that stabilise and deliver naturally derived molecules with measurable bioavailability. The difference between a dossier claim and a clinical result.
Scientific rigour
Scientific rigour
Every Mibelle active is supported by in vitro and in vivo clinical studies, peer-reviewed publications, and marketing claim packages. Regulatory-grade documentation included.
Clean science
Naturally derived platform
Plant-derived sourcing with Ecocert and COSMOS-aligned grades across the portfolio. Vegan and halal-aligned lines available. Science-led natural — not greenwash.
Portfolio
The Mibelle portfolio — stocked and distributed by ADCHEM.
Selected products and families across the shea, canola and coconut platforms.
PhytoCellTec™ Platform
What it is
Beta-Glucan
Primary Use
Anti-ageing, longevity, skin rejuvenation serums and creams
RejuveNAD™
What it is
Sunflower-sprout-derived NAD⁺ booster; naturally derived precursor complex
Primary Use
Skin longevity, holistic anti-ageing, energy-metabolism positioning
AnaGain™
What it is
Organic pea sprout extract; targets the dermal papilla and hair growth signalling
Primary Use
Hair growth, anti-hair-loss, scalp-health formulations
DracoBelle™ Nu
What it is
Moldavian dragonhead extract; collagen-stimulating and skin-density active
Primary Use
Collagen stimulation, hydration, dermis-density and firming claims
CALMandrin
What it is
Soothing botanical active blend; anti-inflammaging mechanism
Primary Use
Sensitive skin, post-procedure care, anti-redness and calming formulations
Beta-Glucan
What it is
High-purity oat beta-glucan; skin barrier-repairing and soothing polymer
Primary Use
Skin barrier support, hydration, soothing — broad formulation compatibility
APPLICATION AREAS
Three decades of plant science in a bottle.
Anti-ageing serums & creams
PhytoCellTec™ and RejuveNAD™ for premium positioning on longevity, skin rejuvenation, and NAD⁺ metabolism. Clinical data supports in-market claims.
Pass — Criterion A
RejuveNAD™
Hair-growth & scalp-health
AnaGain™ for hair growth claim substantiation — clinically demonstrated action on dermal papilla signalling and hair cycle regulation.
AnaGain™
Sensitive skin & post-procedure
CALMandrin and Beta-Glucan for barrier repair, redness reduction, and anti-inflammaging formulations suited to compromised and sensitive skin types.
CALMandrin
Beta-Glucan
Premium dermocosmetics
DracoBelle™ Nu for collagen-stimulation and skin-density claims in dermocosmetics — a category where regulatory-grade dossier support is essential.
DracoBelle™ Nu
Beauty-from-within & nutraceuticals
Mibelle's Food & Health division extends the same plant-active expertise into functional capsules and drinks — RejuveNAD™ for beauty-from-within supplement positioning.
RejuveNAD™
Food & Health
Natural & COSMOS-certified
Ecocert and COSMOS-aligned active grades across the portfolio for brands committed to certified natural formulation — without sacrificing clinical efficacy.
COSMOS grades
Ecocert
DOCUMENTATION TO BE HELD
Documentation that supports your submission — not just your specification.
Every Mibelle active is accompanied by a regulatory documentation package designed for use in cosmetic product safety reports (CPSR), product information files (PIF), and market registration dossiers across EU, GCC, and South Asia regulatory frameworks.
Technical and quality
- Technical Data Sheet (TDS)
- Product specification sheet with agreed release limits
- Certificate of Analysis (CoA), batch specific
- Safety Data Sheet (SDS / MSDS) in the language of the destination market
- Stability data and formulation compatibility guidance
- Recommended use levels, incorporation and processing instructions
- Physical characterisation data: appearance, pH, viscosity, particle size where relevant
Composition and safety
- Full INCI declaration with composition breakdown and percentage ranges
- Toxicological summary and safety data suitable for the CPSR safety assessment
- Allergen declaration covering the EU listed fragrance allergens
- Heavy metals and trace impurity statement
- Nanomaterial status statement
- Microbiological specification, and preservative efficacy data where applicable
- 1,4-dioxane, nitrosamine and other process impurity statements where the chemistry requires it
Efficacy and claim support
- In vitro study reports
- Ex vivo and in vivo study reports for actives
- Claim substantiation package mapped to the claims the brand intends to make
- Mechanism of action summary
- Marketing concept and formulation starter material
Certification and origin
- COSMOS and Ecocert certificates for certified grades
- NATRUE certificate where held
- Vegan declaration
- Halal certificate
- Kosher certificate where required by the market
- RSPO certification for palm-derived material
- ISO 16128 natural origin index calculation
- Country of origin declaration
- GMO-free statement
- BSE / TSE-free declaration
Regulatory and market access
- ISO 22716 cosmetic GMP certificate for the manufacturing site
- REACH registration status statement
- China compliance and IECIC listing statement
- Compliance statement against the restricted and prohibited substance annexes of the destination market
- Microplastic-free statement
- Animal testing position statement
- Change notification and supply continuity commitment
WORKING WITH ADCHEM
What ADCHEM adds to the AAK relationship.
LIKE-FOR-LIKE VALIDATION
Substitution done on performance, not viscosity
Matching an incumbent silicone means matching spreading, volatility, and finish, not just the number on the datasheet. Our laboratories run the comparison before you commit to a changeover.
FORMULATION ECONOMICS
Cost engineering without sensory loss
Silicone is often the largest single cost line in a premium formula. We identify where a grade change genuinely saves money and where it will be noticed by the consumer.
DUAL-SOURCING SUPPORT
Supply continuity planning
Silicone markets tighten periodically. Backing a formula with an integrated producer, and qualifying the grade in advance, is the practical hedge.
AUTO-ATTACHED VIA COSMO
Full documentation with every sample
TDS, SDS, CoA, INCI statement and applicable certificates dispatched with the sample as standard, via COSMO, our digital platform.
On this page
Quick facts
HQ
Buchs, Switzerland
Founded
1991
Segment
Cosmetics & Personal Care
Global reach
50+ countries
ADCHEM regions
MENA · GCC · Türkiye · South Asia
Swiss actives. Regional supply. Technical support included.
Three ways to start — a sample, a TDS, or a conversation with a specialist who knows the chemistry before they discuss the logistics.
Request a Sample
Any product in the portfolio
Download a TDS
Full technical library
Talk to Our Specialist
Someone who knows the chemistry first
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